14 Xie-Huang Sheng # , Lin-Song Teng # , Xiang-Shuai Meng# , Yuan-Hao Song , Zhao-Hua Liu, Jing-Wen Sun, Deng-Feng Wu, Jian-Ping Ma*, Lei Zhang* Discovery of 8-hydroxy- tetrahydroquinoline ferroptosis inhibitors for the treatment of acute kidney injury. Bioorganic Chemistry 164(2025), 108874 13 Lin-Song Teng# , Zhen-Dong Ying# , Xiao-Han Sun#, Hao-Cheng Hou, Shi-Dong Qiu , Peng Liu, Ke-Jing Li , Lei Zhang* , Xie-Huang Sheng* Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury. Chemico-Biological Interactions 421 (2025), 111724 12 Xie-Huang Sheng#, Li-Cong Han#, Ao Gong#, Xiang-Shuai Meng#, Xin-Hui Wang, Lin-Song Teng, Xiao-Han Sun, Kuo-Chen Xu, Zhao-Hua Liu, Ting Wang*, Jian-Ping Ma*, and Lei Zhang*, 'Discovery of Novel Ortho-Aminophenol Derivatives Targeting Lipid Peroxidation with Potent Antiferroptotic Activities', Journal of Medicinal Chemistry, 67 (2024), 9536-51. 11 Xie-Huang Sheng#, Li-Cong Han#, Xiao-Jie Ma#, Ao Gong, Meng-Zhu Hao, Hao Zhu, Xiang-Shuai Meng, Ting Wang, Chang-Hua Sun, Jian-Ping Ma*, and Lei Zhang*, 'Design, Synthesis, and Biological Evaluation of 2-Amino-6-Methyl-Phenol Derivatives Targeting Lipid Peroxidation with Potent Anti-Ferroptotic Activities', European Journal of Medicinal Chemistry, 264 (2024), 115997. 10 Yuan-Hao Song#, Hong-Xu Lei#, Dou Yu#, Hao Zhu, Meng-Zhu Hao, Rong-Hua Cui, Xiang-Shuai Meng, Xie-Huang Sheng*, and Lei Zhang*, 'Endogenous Chemicals Guard Health through Inhibiting Ferroptotic Cell Death', BioFactors, 50 (2024), 266-93. 9 Zhipei Gao, Yongli Du*, Xiehuang Sheng*, and Jingkang Shen, 'Molecular Dynamics Simulations Based on 1-Phenyl-4-Benzoyl-1-Hydro-Triazole Errα Inverse Agonists', International Journal of Molecular Sciences, 22 (2021), 3724. 8 Han Lv, Yongli Du*, Xiehuang Sheng*, Zhipei Gao, and Jingkang Shen, 'Molecular Modeling Studies of [4-(3h-Benzoimidazol-5-Yl)-Pyrimidin-2-Yl]-Amine-Based Cdk4 Inhibitors', Future Medicinal Chemistry, 13 (2021), 1317-39. 7 Zi-Jing Zhao#, Xin-Ying Gao#, Jia-Cheng Zeng, Shao-Long Zhang, Xian-Mai Meng, Yan-Jun Shen, and Xie-Huang Sheng*, 'Theoretical Insights into the Cotransport Mechanism of Gsh with Anticancer Drugs by Mrp1', The Journal of Physical Chemistry B, 124 (2020), 9803-11. 6 Hong-Xu Lei#, KaiLi Zhang#, Yu-Xi Qin, Rong-Jian Dong, De-Zhan Chen, HaiFeng Zhou*, and Xie-Huang Sheng*, 'A Quantum-Chemical Approach to Develop Tetrahydroquinoxaline as Potent Ferroptosis Inhibitors', Journal of Molecular Structure (2020), 129485. 5 Wen-Jing Li, Xin-Hui Chen, Jia-Cheng Zeng, Li-Li Duan, Zhao-Hua Liu*, and Xie-Huang Sheng*, 'Theoretical Insight into the Multiple Interactions of Quinazoline Inhibitors with Breast Cancer Resistance Protein (Bcrp/Abcg2)', Journal of Biomolecular Structure and Dynamics, 38 (2020), 4336-43. 4 Yu-Zhen Li, Xiao-Lu Zhou, Bao-Qi Huo, De-Zhan Chen, Zhao-Hua Liu*, and Xie-Huang Sheng*, 'Reactions of the Lipid Hydroperoxides with Aminic Antioxidants: The Influence of Stereoelectronic and Resonance Effects on Hydrogen Atom Transfer', Frontiers in Chemistry, 7 (2019). 3 Yao Wu, Xin-Ying Gao, Xin-Hui Chen, Shao-Long Zhang, Wen-Juan Wang, Xie-Huang Sheng*, and De-Zhan Chen*, 'Fragment-Centric Topographic Mapping Method Guides the Understanding of Abcg2-Inhibitor Interactions', RSC Advances, 9 (2019), 7757-66. 2 Xie-Huang Sheng, Cheng-Cheng Cui, Chao Shan, Yu-Zhen Li, Duo-Hong Sheng, Bin Sun*, and De-Zhan Chen*, 'O-Phenylenediamine: A Privileged Pharmacophore of Ferrostatins for Radical-Trapping Reactivity in Blocking Ferroptosis', Organic & Biomolecular Chemistry, 16 (2018), 3952-60. 1 Xiehuang Sheng, Chao Shan, Jianbiao Liu, Jintong Yang, Bin Sun, and Dezhan Chen*, 'Theoretical Insights into the Mechanism of Ferroptosis Suppression Via Inactivation of a Lipid Peroxide Radical by Liproxstatin-1', Physical Chemistry Chemical Physics, 19 (2017), 13153-59.
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